EZH1 IS AN ANTIPSYCHOTIC-SENSITIVE EPIGENETIC MODULATOR OF SOCIAL AND MOTIVATIONAL BEHAVIOR THAT IS DYSREGULATED IN SCHIZOPHRENIA

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

Background: With the capacity to modulate gene networks in an environmentally-sensitive manner, the role of epigenetic systems in mental disorders has come under intense investigation.Dysregulation of epigenetic effectors, including microRNAs and histone-modifying enzymes, may better explain the role of environmental risk factors and the observed r

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The effect of STDP temporal kernel structure on the learning dynamics of single excitatory and inhibitory synapses.

Spike-Timing Dependent Plasticity (STDP) is characterized by a wide range of temporal kernels.However, much of the theoretical work has focused on a specific kernel - the "temporally asymmetric Hebbian" learning rules.Previous studies linked excitatory STDP to positive feedback that can account for the emergence of response selectivity.Inhibitory p

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Exposures Moved from Work to Home as a Public Health Hazard

There are numerous occupational pollutants originating from a wide variety of industrial areas and working gruvi golden lager environments.These pollutants can be brought inadvertently from workplace to home in various ways and may negatively affect the health of household.In the literature, this situation was known as para-occupational exposures i

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